“CAR-T cell development is expensive and patient-derived tissue is a limited resource. Our aim is to enable 20 to 50 times more experiments to be performed in these conditions.” – Dr M Zagnoni, CEO of Screenin3D

Miniaturisation and increased throughput in screening are key to a faster, more cost-effective delivery of cancer therapies from bench to bedside. In a new publication in IEEE Open Journal of Engineering in Medicine and Biology, Screenin3D OncoChip^3D microfluidic platform was used to test the cytotoxicity of CAR-T cells and combination therapy on miniaturised solid cancer models.

In this publication, the technology showcases a co-culture of cancerous and stromal cells that create a physiologically relevant solid cancer model for the assessment of CAR-T, carboplatin, and anti-PD-L1 antibody therapies.

Read more about the application of OC^3D Single microfluidic chip in the original publication and the EurekAlert press release 

We are excited to announce that Screenin3D pitched at the BioSeed 2022 conference, a landmark investment event for early-stage companies featuring over 80 investors.

Screenin3D microfluidic technology is a game-changing approach for pre-clinical drug and therapy testing. At the Festival of Biologics in Basel, Dr Zagnoni presented a talk on our bespoke Onco-Chip^3D technology used for the screening of combination immunotherapies with CAR-Ts and their off-target cytotoxicity.

ScreenIn3D has been chosen to appear as an innovative company at SLAS2020 in San Diego.

Along with exhibiting, Michele Zagnoni will also be presenting our technology as part of the SLAS Ignite award. The SLAS Ignite Award recognizes the best start-up or emerging company exhibiting within Innovation AveNEW, a specially designated area within the exhibition.

Full details of the conference can be found on the SLAS website – https://www.slas2020.org/

You can also use the interactive floorplan to find where the ScreenIn3D booth will be located.

ScreenIn3D has been awarded the prestigious ELRIG Prize for Innovation in Drug Discovery at their flagship conference Drug Discovery 2019 which recently took place in Liverpool, UK.

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